Most new, high-priced cancer drugs don’t even extend life for 10 weeks

Ars Technica » Scientific Method 2017-02-11

(credit: Derek K. Miller)

Patients, advocates, and care providers are growing increasingly frustrated that new and often very pricey cancer drugs do little to improve patients’ survival, Kaiser Health News reports.

For instance, the 72 cancer therapies approved between 2002 and 2014 only bought patients an extra 2.1 months of life compared with older drugs, researchers have found. And there’s no evidence that two-thirds of the drugs approved in the last two years improve survival at all.

Yet, that doesn’t keep some of those drugs from coming with heavy price tags and concerning side-effects. Among cancer drugs approved in 2016, the average cost for a year’s worth of treatment was $171,000. And like survival, side-effects aren’t always improved with the higher prices. For example, among thyroid cancer patients, those taking the most expensive drug, cabozantinib, had the worst reports of side effects, including diarrhea, fatigue, sleep disturbance, distress, and difficulty remembering.

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