Comparison of Preprint Postings of Randomized Clinical Trials on COVID-19 and Corresponding Published Journal Articles: A Systematic Review

infodocketGARY's bookmarks 2023-01-27

Summary:

Question  How do preprints of randomized clinical trials (RCTs) on COVID-19 differ from their corresponding published journal articles? Findings  In this systematic review of 152 COVID-19 RCT preprints posted in 2021, 119 (78%) were subsequently published in a scientific, peer-reviewed journal. When preprint and journal article pairs were compared, there were differences in terms of outcomes, analyses, results, or conclusions in 65 of 119 studies (55%); however, the main conclusion remained consistent for all but 2 studies (2%). Meaning  These findings suggest that although there were differences in the outcomes, analyses, results, or conclusions between RCT preprint and journal article pairs in most cases, the main conclusion remained consistent for the majority of studies.

Link:

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2800857

From feeds:

Open Access Tracking Project (OATP) » infodocketGARY's bookmarks

Tags:

oa.new oa.preprints oa.clinical_trials oa.scholcomm oa.pandemic oa.journals oa.jama oa.medicine oa.comparisons

Date tagged:

01/27/2023, 15:03

Date published:

01/27/2023, 10:04