Data sharing and reanalysis of randomized controlled trials in leading biomedical journals with a full data sharing policy: survey of studies published in The BMJ and PLOS Medicine | The BMJ

ab1630's bookmarks 2018-02-14

Summary:

Florian Naudet, et al. Abstract: "Objectives: To explore the effectiveness of data sharing by randomized controlled trials (RCTs) in journals with a full data sharing policy and to describe potential difficulties encountered in the process of performing reanalyses of the primary outcomes.

Design: Survey of published RCTs. ... 

Results: 37 RCTs (21 from The BMJ and 16 from PLOS Medicine) published between 2013 and 2016 met the eligibility criteria. 17/37 (46%, 95% confidence interval 30% to 62%) satisfied the definition of data availability and 14 of the 17 (82%, 59% to 94%) were fully reproduced on all their primary outcomes. Of the remaining RCTs, errors were identified in two but reached similar conclusions and one paper did not provide enough information in the Methods section to reproduce the analyses. Difficulties identified included problems in contacting corresponding authors and lack of resources on their behalf in preparing the datasets. In addition, there was a range of different data sharing practices across study groups.

Conclusions: Data availability was not optimal in two journals with a strong policy for data sharing. When investigators shared data, most reanalyses largely reproduced the original results. Data sharing practices need to become more widespread and streamlined to allow meaningful reanalyses and reuse of data...."

Link:

http://www.bmj.com/content/360/bmj.k400

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Tags:

oa.new oa.data oa.surveys oa.stem oa.gold oa.case.journals oa.bmj oa.plos oa.medicine oa.biology oa.policies oa.policies.journals.data oa.journals

Date tagged:

02/14/2018, 16:53

Date published:

02/14/2018, 11:59