BMJ Editorial: Open Science and Reproducible Research

“‘Scientists should communicate the data they collect and the models they create, to allow free and open access, and in ways that are intelligible, assessable and usable for other specialists . . . Where data justify it, scientists should make them available in an appropriate data repository.’ So said the Royal Society last week, in its report Science as an Open Enterprise: Open Data for Open Science. The report calls for more openness among scientists and with the public and media; greater recognition of the value of data gathering, analysis, and communication; common standards for sharing information to make it widely usable; mandatory publishing of data in a reusable form to support findings; more expertise in managing and supporting the use of digital data; and new software tools to analyse data. It is time for a big shift, says the report, from the status quo... A few days earlier the UK government’s working group on expanding access to published research findings, chaired by Janet Finch, recommended a ‘clear policy direction to support publication in open access or hybrid journals, funded by article processing charges, as the main vehicle for the publication of research, especially when it is publicly funded.’ As Finch explains in a podcast interview with BMJ editor Fiona Godlee, access to published articles and access to data are separate matters, but both can potentially benefit the public. Indeed, major funders—including the Wellcome Trust, US National Institutes of Health, and UK Medical Research Council—have jointly stated their belief that ‘making research datasets available to investigators beyond the original research team in a timely and responsible manner, subject to appropriate safeguards, will generate three key benefits: faster progress in improving health, better value for money, and higher quality science.’ These funders do not yet, however, mandate data sharing. They should. The ability of doctors to make the right decisions with patients about the benefits, harms, and costs of treatments and tests depends increasingly on high quality learning and guidance, which, in turn, depend on a robust evidence base that is as complete and as transparent as possible. We cannot rely only on results in published research articles and trial registries because they are often incompletely and selectively reported... Data sharing can greatly increase dissemination, meta-analysis, and understanding of research results; it can also aid confirmation or refutation of research through replication [7],  allow better implementation of research findings [8], and increase transparency about the quality and integrity of research. It does bear some technical challenges and risks: these include potential invasion of participants’ privacy and breaking of patients’ confidentiality, inappropriate data manipulation, compromised academic or commercial primacy, and breach of intellectual property rights and journal copyright, but none of these should be insurmountable [9]. So let’s get on with it. So let’s get on with it. Since 2009 the BMJ has asked authors to state at the end of their article whether they will allow their data to be accessed or even reanalysed by others [10]. Many authors have agreed to share their anonymised data. To make it easy for authors to do this, the BMJ is partnering with the Dryad online repository(http://datadryad.org/), something that our sister journal BMJ Open has been doing for some time. Fifteen datasets from BMJ Open articles are already posted, as well as one from the BMJ [11]. Meanwhile, we are stepping up the BMJ’s commitment to open access. After the success of last year’s pilot, we have introduced article processing fees for all published research articles. With these latest high level UK reports, and the growing support of research funders around the world [4], the move towards open access has reached a tipping point. The BMJ was the first major general medical journal to make research articles freely available online and has maintained its commitment to open access ever since...”