TagTeam hubs

361 - 365 of 409
  • Test hub

    Owners :
    peterh
    Created:
    2017-03-07

  • Testing JSON import

    Owners :
    nathmobile
    Created:
    2013-06-24

    Testing JSON import

  • testing tags conflation

    Owners :
    mikele
    Created:
    2013-06-11

  • The Engine Room

    Owners :
    zararah, thomwithoutanh
    Created:
    2016-10-25

    Everything of interest to people of The Engine Room

  • The Potential Impact of Maintaining a 3-Hour IV Thrombolysis Window: How Many More Patients can we Safely Treat?

    Owners :
    JsciMed
    Created:
    2014-01-30

    The Potential Impact of Maintaining a 3-Hour IV Thrombolysis Window: How Many More Patients can we Safely Treat?

    BACKGROUND:

    In 2008, the European Cooperative Acute Stroke Study-3 (ECASS-3) demonstrated that intravenous-tissue plasminogen activator could be safely administered for acute stroke patients presenting between 3 and 4.5 hours from symptom onset. Recently, the Food and Drug Administration rejected expansion of this time window in the United States. We sought to determine how many fewer patients would be treated by maintaining this restricted time window.

    METHODS:

    We reviewed charts from patients who received intravenous thrombolysis at the University of Alabama at Birmingham between January 2009 and December 2011. Patients were divided into two groups (treated within 3 hours of onset, treated between 3 and 4.5 hours from onset). Demographics, stroke severity and protocol deviations according to the ECASS-3 trial were collected. Our safety measures were any hemorrhagic transformation, symptomatic intracerebral hemorrhage and systemic hemorrhage.

361 - 365 of 409