Melatonin Alleviates Pulmonary Fibrosis Induced by Atrazine Targeting the Pulmonary Capillary Microenvironment

Atrazine (ATZ), a common herbicide, accumulates in water sources, raising concerns about lung hazards from excessive tap water residues. Pulmonary capillary endothelial cells (PCECs) are primary targets of bloodborne toxins. Melatonin (MLT), an endogenous neuroendocrine hormone, shows promise in mitigating lung disease. This study developed a mouse model for studying the pulmonary effects of ATZ through drinking water and the protective effect of MLT. The results indicate that ATZ-induced...