MiR-122-5p promotes peritoneal fibrosis in a rat model of peritoneal dialysis by targeting Smad5 to activate Wnt/β-catenin pathway

pubmed: wnt1 2022-05-14

Summary:

Peritoneal fibrosis (PF) is the main reason leading to declining efficiency and ultrafiltration failure of peritoneum, which restricts the application of peritoneal dialysis (PD). We aimed to investigate the effects and mechanisms of miR-122-5p on the PF. Sprague-Dawley (SD) rats were infused with glucose-based standard PD fluid to establish PF model. HE staining was performed to evaluate the extent of PF. Real-time fluorescence quantitative polymerase chain reaction (RT-qPCR) and fluorescence...

Link:

https://pubmed.ncbi.nlm.nih.gov/35170385/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20220514083854&v=2.17.6

From feeds:

Exome » pubmed: wnt1

Tags:

Authors:

Yirong Liu, Zhihong Ma, Zhenxing Huang, Dongmei Zou, Junbin Li, Ping Feng

Date tagged:

05/14/2022, 08:38

Date published:

02/16/2022, 06:00