Home Exome pubmed: wnt1 Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

Breast cancer metastasis to brain results in recruitment and activation of microglia through annexin-A1/formyl peptide receptor signaling

pubmed: wnt1 2022-06-23

Summary:

CONCLUSIONS: The present study uncovered a network encompassing autocrine/paracrine ANXA1 signaling between metastatic mammary cancer cells and microglia that drives microglial recruitment and activation. Inhibition of ANXA1 and/or its receptor may be therapeutically rewarding in the treatment of breast cancer and secondary metastasis to the brain.

Link:

https://pubmed.ncbi.nlm.nih.gov/35382852/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20220623121703&v=2.17.6

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Exome ยป pubmed: wnt1

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Authors:

Sok Lin Foo, Karishma Sachaphibulkij, Corinne L Y Lee, Gracemary L R Yap, Jianzhou Cui, Thiruma Arumugam, Lina H K Lim

Date tagged:

06/23/2022, 12:17

Date published:

04/06/2022, 06:00