Ethanol Exposure Up-Regulates PD-L1/PD-1 Immune Checkpoint Pathway and Promotes Mammary Tumor Development

pubmed: wnt1 2022-09-23

Summary:

Alcohol consumption in women enhances breast cancer incidence and ethanol is the main causal factor. Compromised host immunity through immunosuppression facilitates the development of many types of cancer, including breast cancer. Immune cells in breast tissues, particularly tumor-infiltrating CD8 cytotoxic T cells, play a critical role in the host anti-tumor immunity against breast tumorigenesis. These cytotoxic T cells are the major immune cells to carry out anti-tumor immunity through their...

Link:

https://pubmed.ncbi.nlm.nih.gov/35756611/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20220923023321&v=2.17.8

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Exome ยป pubmed: wnt1

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Authors:

Wenhua Xu, Linqing Wu, Mei Xu, Jia Luo, Gang Chen

Date tagged:

09/23/2022, 02:33

Date published:

06/27/2022, 06:00