BMP suppresses WNT to integrate patterning of orthogonal body axes in adult planarians

pubmed: wnt1 2023-12-03

Summary:

Adult regeneration restores patterning of orthogonal body axes after damage in a post-embryonic context. Planarians regenerate using distinct body-wide signals primarily regulating each axis dimension: anteroposterior Wnts, dorsoventral BMP, and mediolateral Wnt5 and Slit determinants. How regeneration can coordinate perpendicular tissue axes without symmetry-breaking embryonic events is not fully understood. Here, we report that the planarian dorsoventral regulator bmp4 suppresses the posterior...

Link:

https://pubmed.ncbi.nlm.nih.gov/37729232/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20231203204604&v=2.17.9.post6+86293ac

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Exome ยป pubmed: wnt1

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Authors:

Eleanor G Clark, Christian P Petersen

Date tagged:

12/03/2023, 20:46

Date published:

09/20/2023, 06:00