Encyclopedia of Proteome Dynamics: a big data ecosystem for (prote)omics | Nucleic Acids Research | Oxford Academic

ab1630's bookmarks 2018-01-14

Summary:

"Abstract: Driven by improvements in speed and resolution of mass spectrometers (MS), the field of proteomics, which involves the large-scale detection and analysis of proteins in cells, tissues and organisms, continues to expand in scale and complexity. There is a resulting growth in datasets of both raw MS files and processed peptide and protein identifications. MS-based proteomics technology is also used increasingly to measure additional protein properties affecting cellular function and disease mechanisms, including post-translational modifications, protein–protein interactions, subcellular and tissue distributions. Consequently, biologists and clinicians need innovative tools to conveniently analyse, visualize and explore such large, complex proteomics data and to integrate it with genomics and other related large-scale datasets. We have created the Encyclopedia of Proteome Dynamics (EPD) to meet this need (https://peptracker.com/epd/). The EPD combines a polyglot persistent database and web-application that provides open access to integrated proteomics data for >30 000 proteins from published studies on human cells and model organisms. It is designed to provide a user-friendly interface, featuring graphical navigation with interactive visualizations that facilitate powerful data exploration in an intuitive manner. The EPD offers a flexible and scalable ecosystem to integrate proteomics data with genomics information, RNA expression and other related, large-scale datasets."

Link:

https://academic.oup.com/nar/article/46/D1/D1202/4107223

From feeds:

Open Access Tracking Project (OATP) » ab1630's bookmarks

Tags:

oa.new oa.data oa.stem oa.biology oa.open_science oa.green oa.scholcomm oa.genres oa.dynamic oa.repositories

Date tagged:

01/14/2018, 15:55

Date published:

01/14/2018, 10:55