Postoperative Complication Rates after One-Level Cervical Spine Surgery in Patients with Parkinson's Disease: A Database Study

database[Title] 2022-07-01

World Neurosurg. 2022 Jun 22:S1878-8750(22)00866-X. doi: 10.1016/j.wneu.2022.06.081. Online ahead of print.

ABSTRACT

OBJECTIVE: Parkinson's Disease (PD) is a risk factor for worse surgical outcomes. The degree to which Parkinson's affects outcomes in cervical spine surgery is not well understood. Therefore, we characterize rates of postoperative complications among patients with PD who undergo cervical spine surgery.

METHODS: Using the PearlDiver Database, we identified patients who underwent one-level anterior cervical discectomy and fusion (ACDF), posterior cervical fusions (PCF), or discectomy/decompressions with concomitant PD between 2011-2019. Patients with PD who underwent surgery and had one year follow up were included. Complications 30-, 60-, and 90-days after surgery were identified and aggregated into body systems (respiratory, gastrointestinal, etc.). Comparison controls without concomitant PD who received c-spine surgery were matched for age, sex, and comorbidities.

RESULTS: 259,443 ACDFs, 30,929 PCFs, and 29,563 decompressions were identified. Of the above procedures, 1,117 were performed on patients with PD (0.35%). Highest 90-day complications rates in patients with PD were pulmonary and gastrointestinal related (6.05%) in those who received ACDF, neuro related (8.51%) in those who received PCF, and genitourinary related (8.76%) in those that received a decompression. Compared to patients without PD, post-operative complications rates were similar and not significantly different.

CONCLUSION: Patients with PD who receive ACDF have higher rates of pulmonary (6.05%), neurological (5.24%), and psychiatric (3.23%) complications at 90 days. The differences did not reach statistical significance. This suggests that patients with PD do not experience higher rates of acute, postoperative complications when undergoing one level cervical spine surgery.

PMID:35752419 | DOI:10.1016/j.wneu.2022.06.081