Silicon Therapeutics Announces Recipient of the First Open Science Fellowship | Business Wire

"Silicon Therapeutics, an integrated computational drug discovery company creating novel small molecule therapeutics for diseases with challenging protein targets, is pleased to announce that the first Open Science Fellowship will be awarded the laboratory of Dr. John D. Chodera at Memorial Sloan Kettering Cancer Center (MSK). The fellowship is designed to advance the open science movement within the drug discovery industry, facilitating access to scientific knowledge, methods, and data. Patrick Grinaway, a graduate student in the Chodera Lab, will lead the development efforts of the project, entitled 'Development of efficient open source free energy-based lead optimization algorithms.' The work will build upon the open source GPU-accelerated OpenMM molecular simulation platform to develop advanced relative binding free energy methods, which can be used for predicting the binding affinity and selectivity of ligands to targets."