Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity

pubmed: wnt1 2024-05-21

Summary:

CONCLUSIONS: The absence of primary cilia due to Ift46 deficiency in NCCs is associated with anterior segment dysgenesis (ASD) and corneal neovascularization, suggesting a potential link to Axenfeld-Rieger syndrome, a disorder characterized by ASD. This underscores the pivotal role of primary cilia in ensuring proper anterior segment development and maintaining an avascular cornea.

Link:

https://pubmed.ncbi.nlm.nih.gov/38517430/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20240521041816&v=2.18.0.post9+e462414

From feeds:

Exome ยป pubmed: wnt1

Tags:

Authors:

Seungwoon Seo, Seong Keun Sonn, Hyae Yon Kweon, Jing Jin, Tsutomu Kume, Je Yeong Ko, Jong Hoon Park, Goo Taeg Oh

Date tagged:

05/21/2024, 04:18

Date published:

03/22/2024, 06:00