The antifibrotic potential of IMT504: modulation of GLAST + Wnt1 + bone marrow stromal progenitors and hepatic microenvironment

pubmed: wnt1 2024-11-14

Summary:

CONCLUSION: In summary, our findings identify IMT504 as a promising candidate molecule with potent antifibrotic properties, operating through both direct and indirect mechanisms, including the activation of GLAST + Wnt1 + BMSPs.

Link:

https://pubmed.ncbi.nlm.nih.gov/39227908/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20241114020218&v=2.18.0.post9+e462414

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Exome » pubmed: wnt1

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Authors:

Maximiliano Borda, Romina Sierra, María José Cantero, Sofía Gómez Bustillo, Esteban Juan Fiore, Gianlucca Giardelli, Matías Martino Garcet, María Luz Rebottaro, Juan Miguel Bayo Fina, Máximo Schiavone, Julia Rubione, Mariana Gabriela García, Alejandro Montaner, Guillermo Daniel Mazzolini, Jorge Benjamín Aquino

Date tagged:

11/14/2024, 02:02

Date published:

09/03/2024, 06:00