Dally-like Is Unlike Dally in Assisting Wingless Spread.
pubmed: wnt1 2021-02-20
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Dally-like Is Unlike Dally in Assisting Wingless Spread.
Dev Cell. 2020 09 14;54(5):572-573
Authors: Grobe K, Guerrero I
Abstract Lipidated morphogens can spread within tissues to regulate cell fate during development or tissue repair. How these insoluble molecules reach distant target cells remains unclear. Reporting in Nature, McGough et al. (2020) reveal the secret of how the cell-surface proteoglycan Dally-like-protein (Dlp) promotes long-range signaling of the palmitoylated morphogen Wingless.
PMID: 32931749 [PubMed - indexed for MEDLINE]