Interleukin-6 (IL-6) deficiency enhances intramembranous osteogenesis following stress fracture in mice

pubmed: wnt1 2021-03-04

Summary:

Interleukin-6 (IL-6) is highly upregulated in response to skeletal injury, suggesting it plays a role in the inflammatory phase of fracture repair. However, the impact of IL-6 on successful repair remains incompletely defined. Therefore, we investigated the role of IL-6 in two models of fracture repair (full fracture and stress fracture) using 12-week old IL-6 global knockout mice (IL-6 KO) and wild type (WT) littermate controls. Callus morphology and mineral density 14 days after full femur...

Link:

https://pubmed.ncbi.nlm.nih.gov/33181349/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20210304075041&v=2.14.2

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Exome ยป pubmed: wnt1

Tags:

Authors:

Brandon A Coates, Jennifer A McKenzie, Susumu Yoneda, Matthew J Silva

Date tagged:

03/04/2021, 07:58

Date published:

11/12/2020, 06:00