Effect and mechanism of miR-217 on drug resistance, invasion and metastasis of ovarian cancer cells through a regulatory axis of CUL4B gene silencing/inhibited Wnt/β-catenin signaling pathway activation

pubmed: wnt1 2021-05-27

Summary:

CONCLUSIONS: CUL4B gene is the target gene of miR-217. MiR-217 can silence the expression of this gene, and inhibit the activation of Wnt/β-catenin signaling pathway to enhance the cisplatin sensitivity and reverse drug resistance, inhibit cell invasion and migration, and promote cell apoptosis.

Link:

https://pubmed.ncbi.nlm.nih.gov/33506897/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20210527091707&v=2.14.4

From feeds:

Exome » pubmed: wnt1

Tags:

Authors:

H-R Liu, J Zhao

Date tagged:

05/27/2021, 09:17

Date published:

01/28/2021, 06:00