Data-Driven Approaches to Maximize the Impact of Pediatric Clinical Trials | Pediatrics | American Academy of Pediatrics

"The study also revealed that the timely dissemination of pediatric trial results through deposit in trial registries and publication in peer-reviewed journals, remains suboptimal. At 3 years since trial completion, only 23% of trials had results available in ClinicalTrials.gov and 39% had been published. Particularly notable is that compared with trials receiving funding from either industry or government entities, those sponsored by academic institutions were least likely to have results disseminated after trial completion (45% compared with 61% for trials with industry funding and 59% for those with government funding). This is consistent with prior studies demonstrating poor performance and marked variation in results reporting by academic medical centers across the US.⁴ While timely dissemination of research results represents a core mission of academic institutions, effective enforcement mechanisms are lacking. Closer monitoring of publication and reporting activities for pediatric clinical trials is warranted to reduce loss of scientific information and breaches in commitments to participating patients and families.⁵ "