Functionality of bone marrow mesenchymal stromal cells derived from head and neck cancer patients - A FDA-IND enabling study regarding MSC-based treatments for radiation-induced xerostomia

pubmed: wnt1 2024-04-23

Summary:

CONCLUSIONS: MSC (M) from previously treated HNC patients can be expanded for auto-transplantation and are functionally active. Furthermore IFNγ-stimulated MSC(M) express proteins implicated in salivary gland regeneration. This study provides preliminary data supporting the feasibility of using autologous MSC(M) from HNC patients to treat RT-induced salivary dysfunction.

Link:

https://pubmed.ncbi.nlm.nih.gov/38224919/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20240423234128&v=2.18.0.post9+e462414

From feeds:

Exome » pubmed: wnt1

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Authors:

Grace C Blitzer, Cristina Paz, Annemarie Glassey, Olga R Ganz, Jayeeta Giri, Andrea Pennati, Ross O Meyers, Amber M Bates, Kwangok P Nickel, Marissa Weiss, Zachary S Morris, Ryan J Mattison, Kimberly A McDowell, Emma Croxford, Richard J Chappell, Tiffany A Glazer, Nicole M Rogus-Pulia, Jacques Galipeau, Randall J Kimple

Date tagged:

04/23/2024, 23:44

Date published:

01/15/2024, 06:00