GPR97 deficiency suppresses Wnt/β-catenin signaling in hypertensive nephropathy

pubmed: wnt1 2024-05-15

Summary:

Accumulating evidence shows that renal fibrosis plays a key role in the development of hypertensive nephropathy (HTN). Therefore, a better understanding of the underlying mechanism of renal fibrosis regulation in HTN would be critical for designing rational strategies for therapeutic interventions. In this study, we revealed that GPR97, a novel identified adhesion G coupled receptor, plays an important role in the regulation of Wnt/β-catenin signaling, which is the crucial driver of renal...

Link:

https://pubmed.ncbi.nlm.nih.gov/38345813/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20240515173532&v=2.18.0.post9+e462414

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Authors:

Ping Gao, Jinghan Zhu, Guo Xiangyun, Jing Li, Jichao Wu

Date tagged:

05/15/2024, 17:35

Date published:

02/12/2024, 06:00