Sequencing Reveals miRNAs Enriched in the Developing Mouse Enteric Nervous System

pubmed: wnt1 2024-05-26

Summary:

The enteric nervous system (ENS) is an essential network of neurons and glia in the bowel wall. Defects in ENS development can result in Hirschsprung disease (HSCR), a life-threatening condition characterized by severe constipation, abdominal distention, bilious vomiting, and failure to thrive. A growing body of literature connects HSCR to alterations in miRNA expression, but there are limited data on the normal miRNA landscape in the developing ENS. We sequenced small RNAs (smRNA-seq) and...

Link:

https://pubmed.ncbi.nlm.nih.gov/38250801/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20240526104703&v=2.18.0.post9+e462414

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Exome ยป pubmed: wnt1

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Authors:

Christopher Pai, Rajarshi Sengupta, Robert O Heuckeroth

Date tagged:

05/26/2024, 10:47

Date published:

01/22/2024, 06:00