Oxidative DNA damage promotes vascular aging associated with changes in extracellular matrix-regulating proteins

pubmed: wnt1 2024-05-26

Summary:

CONCLUSIONS: Vascular aging is associated with oxidative DNA damage, downregulation of major BER proteins, and changes in multiple ECM structural and regulatory proteins. Ogg1 protects against vascular aging, associated with changes in ECM regulatory proteins including LOX and WISP2.

Link:

https://pubmed.ncbi.nlm.nih.gov/38717632/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20240526110838&v=2.18.0.post9+e462414

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Exome ยป pubmed: wnt1

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Authors:

Kirsty Foote, Marieke Rienks, Lukas Schmidt, Konstantinos Theofilatos, None Yasmin, Matiss Ozols, Alexander Eckersley, Aarti Shah, Nichola Figg, Alison Finigan, Kevin O'Shaughnessy, Ian B Wilkinson, Manuel Mayr, Martin Bennett

Date tagged:

05/26/2024, 11:08

Date published:

05/08/2024, 06:00