Xihuang pills targeting the Warburg effect through inhibition of the Wnt/β-catenin pathway in prostate cancer
pubmed: wnt1 2024-08-11
Summary:
CONCLUSION: XHP demonstrated remarkable efficacy in suppressing the growth, proliferation, apoptosis, migration, and invasiveness of prostate tumors. The interaction between XHP's active constituents and Wnt1 was evident, leading to the inhibition of Wnt1 and downstream anti-carcinogenic factors, thereby influencing the β-catenin/HIF-1α-mediated glycolysis.