The TGF-β1 target WISP1 is highly expressed in liver cirrhosis and cirrhotic HCC microenvironment and involved in pro- and anti-tumorigenic effects

pubmed: wnt1 2024-11-11

Summary:

CONCLUSIONS: WISP1 expression is induced by TGF-β1 in hepatocytes and is associated with cirrhotic liver disease. We propose a crucial role of WISP1 in balancing pro- and anti-tumorigenic effects during premalignant stages of CLD.

Link:

https://pubmed.ncbi.nlm.nih.gov/39033550/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20241111221324&v=2.18.0.post9+e462414

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Exome » pubmed: wnt1

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Authors:

Anne Dropmann, Sophie Alex, Katharina Schorn, Chenhao Tong, Tiziana Caccamo, Patricio Godoy, Iryna Ilkavets, Roman Liebe, Daniela Gonzalez, Jan G Hengstler, Albrecht Piiper, Luca Quagliata, Matthias S Matter, Oliver Waidmann, Fabian Finkelmeier, Teng Feng, Thomas S Weiss, Nuh Rahbari, Emrullah Birgin, Erik Rasbach, Stephanie Roessler, Kai Breuhahn, Marcell Tóth, Matthias P Ebert, Steven Dooley, Seddik Hammad, Nadja M Meindl-Beinker

Date tagged:

11/11/2024, 22:16

Date published:

07/21/2024, 06:00