Conditional heterozygous loss of Kit receptor tyrosine kinase in neural crest cell lineage is associated with midline cleft lip and bifid nose deformity
pubmed: wnt1 2024-12-21
Summary:
CONCLUSION: Conditional heterozygous loss of Kit in Wnt1-Cre; Kit^(2lox/+) embryos is associated with craniofacial dysplasia and exhibit defective NC development in vitro and in vivo.