Early-Onset Osteoporosis: Molecular Analysis in Large Cohort and Focus on the PLS3 Gene

pubmed: wnt1 2024-12-21

Summary:

Osteoporosis is a skeletal disorder characterized by abnormal bone microarchitecture and low bone mineral density (BMD), responsible for an increased risk of fractures and skeletal fragility. It is a common pathology of the aging population. However, when osteoporosis occurs in children or young adults, it strongly suggests an underlying genetic etiology. Over the past two decades, several genes have been identified as responsible for this particular kind of considered monogenic early-onset...

Link:

https://pubmed.ncbi.nlm.nih.gov/39316135/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20241221040950&v=2.18.0.post9+e462414

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Exome » pubmed: wnt1

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Authors:

Maxence Mancini, Roland Chapurlat, Bertrand Isidor, Marine Desjonqueres, Guillaume Couture, Pascal Guggenbuhl, Régis Coutant, Salima El Chehadeh, Mélanie Fradin, Aline Frazier, Alice Goldenberg, Pascaline Guillot, Eugénie Koumakis, Nadia Mehsen-Cêtre, Massimiliano Rossi, Élise Schaefer, Sabine Sigaudy, Valérie Porquet-Bordes, Élisabeth Fontanges, Pauline Letard, Thomas Edouard, Rose-Marie Javier, Martine Cohen-Solal, Thomas Funck-Brentano, Corinne Collet

Date tagged:

12/21/2024, 04:09

Date published:

09/24/2024, 06:00