Efficacy of the Bushen Jianpi Huoxue Formula on Beclin-1/Bcl-2-mediated autophagy and apoptosis in osteoblasts

pubmed: wnt1 2025-01-25

Summary:

CONCLUSION: Bushen Jianpi Huoxue Formula effectively enhanced the osteogenic activity by inhibiting Beclin-1-induced autophagy instead of the binding of Beclin-1 and Bcl-2. This underscores the formula's multifaceted role in promoting bone health and managing cellular stress, and offers novel insights into its therapeutic potential against osteoporosis.

Link:

https://pubmed.ncbi.nlm.nih.gov/39834809/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20250125104538&v=2.18.0.post9+e462414

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Exome ยป pubmed: wnt1

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Authors:

Yanping Lin, Rui Zhao, Jiachun Huang, Tongying Chen, Haolin Yang, Haiwei Guo, Lei Wan, Zhihai Zhang, Ying Li, Genfu Zhu, Hongxing Huang

Date tagged:

01/25/2025, 10:45

Date published:

01/21/2025, 06:00