Metabolic Syndrome Develops Cardia Cancer via Nuclear Factor-E2-related Factor 2-Programmed Death-Ligand 1 Signaling

pubmed: wnt1 2025-12-09

Summary:

CONCLUSIONS: HFD-related metabolic endotoxemia may promote GCA progression via PD-L1 induction in tumor cells directly through Nrf2 signaling activated by LPS and through NFκB signaling by TNF-α from LPS-activated macrophages in tumor microenvironment.

Link:

https://pubmed.ncbi.nlm.nih.gov/40935246/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20251209153652&v=2.18.0.post22+67771e2

From feeds:

Exome » pubmed: wnt1

Authors:

Keisuke Kusano, Kaname Uno, Toru Tamahara, Naoki Asano, Koichiro Sudo, Mizuki Tanabe, Koya Ogasawara, Takeshi Kanno, Tomoyuki Koike, Ritsuko Shimizu, Atsushi Masamune

Date tagged:

12/09/2025, 15:36

Date published:

09/11/2025, 06:00