Knockdown of ITGA2 Promotes Pyroptosis in Thyroid Cancer by Regulating the DNA Damage Response

pubmed: wnt1 2025-12-10

Summary:

CONCLUSION: ITGA2 promotes TC progression by regulating the DNA damage response and inhibiting pyroptosis. Knockdown of ITGA2 increases oxidative stress, exacerbates DNA damage, and inhibits the Wnt/β-catenin pathway, indicating it may have potential as a treatment target in TC.

Link:

https://pubmed.ncbi.nlm.nih.gov/40917053/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20251210184247&v=2.18.0.post22+67771e2

From feeds:

Exome » pubmed: wnt1

Authors:

Liang Yan, Dongming Hua, Rong Ying, Xiaoshuang Liu, Jun Jiang, Zhaolong Liu, Yu Feng

Date tagged:

12/10/2025, 18:42

Date published:

09/08/2025, 06:00