Additive effects on craniofacial development upon conditional ablation of PDGFRα and SHP2 in the mouse neural crest lineage

pubmed: wnt1 2025-12-14

Summary:

CONCLUSIONS: We propose a putative model in which SHP2 binds and dephosphorylates PDGFRα while simultaneously increasing survival through an Erk1/2-independent mechanism.

Link:

https://pubmed.ncbi.nlm.nih.gov/41246925/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20251214144121&v=2.18.0.post22+67771e2

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Exome » pubmed: wnt1

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Authors:

Daniel Fuhr, Jessica Johnston, Elliott P Brooks, Katherine A Fantauzzo

Date tagged:

12/14/2025, 14:41

Date published:

11/17/2025, 06:00