Glabridin attenuates dibutyl phthalate-induced testicular toxicity via regulating oxidative stress, inflammation, apoptosis, and Wnt/β-catenin pathway

pubmed: wnt1 2025-12-15

Summary:

Dibutyl phthalate (DBP) is a member of phthalate esters which are considered as potent environmental toxicant owing to their damaging effects on different organs including testis. Glabridin (GLN) is a polyphenolic substance that is found in the roots of Glycyrrhiza glabra and exhibits a wide range of pharmacological activities. This research investigation explored the ameliorative potential of GLN against DBP instigated testicular toxicity. Forty-eight male Sprague Dawley rats were categorized...

Link:

https://pubmed.ncbi.nlm.nih.gov/41240790/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20251215122837&v=2.18.0.post22+67771e2

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Authors:

Hesham M Hassan, Hafsa Ashfaq, Fuad M Alzahrani, Khalid J Alzahrani, Abrar Aljohani

Date tagged:

12/15/2025, 12:29

Date published:

11/15/2025, 06:00