PIWI-interacting RNA-ame-1128833 targets honeybee Yes-associated protein 1 (AmYAP1) to modulate gut growth and developmental gene expression in honeybee larvae

Beyond their classical role in preserving germline genome integrity via transposon silencing, piRNAs are increasingly recognized as pivotal regulators in somatic tissues. In these contexts, piRNAs orchestrate essential processes such as gut growth, gene expression regulation, metabolism, and the maintenance of intestinal homeostasis. Based on deep sequencing and bioinformatics, piR-ame-1128833 was previously detected to be significantly up-regulated. Here, we characterized the regulatory...