Comparative Transcriptome and Gene-Editing Analyses Reveal the Molecular Mechanism of Albinism in the Taiwanese Loach

The Taiwanese loach (Paramisgurnus dabryanus ssp. Taiwanese), known for its nutritional and ornamental qualities, exhibits a rare form of albinism. Specifically, certain individuals display golden-pink eyes and a golden-red body color devoid of blotches, thereby attracting consumers. However, the principal genes regulating this phenotype remain unidentified. Consequently, this study conducted a transcriptome comparative analysis of the skin between wild-type (M) and mutant (N) Taiwanese loaches....