SIRT1 enhances alveolar bone repair by regulating glycolytic metabolism via the Wnt/β-catenin pathway

The repair of alveolar bone is of vital importance for maintaining oral health and promoting recovery following injury or disease. Functioning as an NAD+-dependent protein deacetylase, SIRT1 modulates diverse physiological activities, with particular relevance to metabolism and osteogenesis. However, its specific role in alveolar bone repair and the associated metabolic pathways have not been fully elucidated. In this study, we explored the function of SIRT1 in alveolar bone healing using a...