Crosstalk between WNT and STAT3 is mediated by galectin-3 in tumor progression
pubmed: wnt1 2021-06-22
Summary:
CONCLUSIONS: We propose that galectin-3 mediates the crosstalk between the WNT and STAT3 signaling pathways. Therefore GB1107, a galectin-3-specific inhibitor, maybe a potent agent with anti-gastric cancer activity. Further studies are needed for its clinical application in gastric cancer therapy.