RERE deficiency contributes to the development of orofacial clefts in humans and mice

pubmed: wnt1 2021-06-23

Summary:

Deletions of chromosome 1p36 are the most common telomeric deletions in humans and are associated with an increased risk of orofacial clefting. Deletion/phenotype mapping, combined with data from human and mouse studies, suggests the existence of multiple 1p36 genes associated with orofacial clefting including SKI, PRDM16, PAX7 and GRHL3. The arginine-glutamic acid dipeptide (RE) repeats gene (RERE) is located in the proximal critical region for 1p36 deletion syndrome and encodes a nuclear...

Link:

https://pubmed.ncbi.nlm.nih.gov/33772547/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20210623054519&v=2.14.4

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Exome ยป pubmed: wnt1

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Authors:

Bum Jun Kim, Hitisha P Zaveri, Peter N Kundert, Valerie K Jordan, Tiana M Scott, Jenny Carmichael, Daryl A Scott

Date tagged:

06/23/2021, 05:45

Date published:

03/27/2021, 06:00