Regulation of IL-6/STAT-3/Wnt axis by nifuroxazide dampens colon ulcer in acetic acid-induced ulcerative colitis model: Novel mechanistic insight

pubmed: wnt1 2021-06-23

Summary:

AIM: Ulcerative colitis (UC) is a common intestinal problem characterized by the diffusion of colon inflammation and immunity dysregulation. Nifuroxazide, a potent STAT-3 inhibitor, exhibits diverse pharmacological properties. The present study aimed to elucidate a novel anti-colitis mechanism of nifuroxazide against the acetic acid-induced UC model.

Link:

https://pubmed.ncbi.nlm.nih.gov/33794250/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20210623102200&v=2.14.4

From feeds:

Exome » pubmed: wnt1

Authors:

Fares E M Ali, Mohamed M Elfiky, Walaa A Fadda, Howaida S Ali, Amany Refaat Mahmoud, Zuhair M Mohammedsaleh, Tarek Hamdy Abd-Elhamid

Date tagged:

06/23/2021, 10:24

Date published:

04/01/2021, 06:00