Linagliptin Protects Human SH-SY5Y Neuroblastoma Cells against Amyloid-beta Cytotoxicity via the Activation of Wnt1 and Suppression of IL-6 Release
pubmed: wnt1 2021-08-29
Summary:
CONCLUSION: The current findings reveal that linagliptin alleviates Aβ1-42-induced inflammation in SH-SY5Y cells, probably through the suppression of IL-6 release, and some of its benefits are mediated through the activation of the Wnt1 signaling pathway.