Secreted frizzled-related protein 4 exerts anti-atherosclerotic effects by reducing inflammation and oxidative stress

pubmed: wnt1 2022-06-23


Atherosclerosis and its sequelae, such as coronary artery disease (CAD), are the most common diseases worldwide and the leading causes of morbidity and mortality in most countries. Our previous studies have shown that circulating secreted frizzled-related protein 4 (SFRP4) levels are increased in patients with CAD. However, the role of SFRP4 in the development of atherosclerosis remains unclear; thus, the purpose of this study was to determine the effect of SFRP4 on high-fat diet (HFD)-induced...


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Exome ยป pubmed: wnt1



Jianwei Zhang, Zicong Yang, Zhishan Liang, Mengjie Wang, Changxing Hu, Chao Chang, Lei Shi, Qingwei Ji, Ling Liu

Date tagged:

06/23/2022, 12:17

Date published:

04/01/2022, 06:00