Sclerostin Suppression Facilitates Uveal Melanoma Progression Through Activating Wnt/β-Catenin Signaling <em>Via</em> Binding to Membrane Receptors LRP5/LRP6
pubmed: wnt1 2022-09-19
Summary:
CONCLUSION: SOST silencing may facilitate the malignant progression of UM cells through activating Wnt/β-catenin signaling. Mechanistically, SOST may exert this function by interacting with LRP5/LRP6 membrane receptors.