Home Exome pubmed: wnt1 WNT1-inducible signalling pathway protein 1 stabilizes atherosclerotic plaques in apolipoprotein-E-deficient mice via the focal adhesion kinase/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase pathway

WNT1-inducible signalling pathway protein 1 stabilizes atherosclerotic plaques in apolipoprotein-E-deficient mice via the focal adhesion kinase/mitogen-activated extracellular signal-regulated kinase/extracellular signal-regulated kinase pathway

pubmed: wnt1 2022-11-24

Summary:

CONCLUSION: WISP1 not only inhibits the apoptosis of VSMCs via the PI3K/Akt/mTOR pathway but also enhances the migration and proliferation of VSMCs via the integrin α5β1 and FAK/MEK/ERK pathways. Therefore, WISP1 could enhance the stability of atherosclerotic plaques.

Link:

https://pubmed.ncbi.nlm.nih.gov/35881419/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20221124144854&v=2.17.8

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Exome » pubmed: wnt1

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Authors:

Dian Liu, Mingjun Zhang, Jingjing Tian, Mingxiao Gao, Ming Liu, Xiangrui Fu, Tao Jin, Jinyu Pan, Fangna Chen, Fengshuang An

Date tagged:

11/24/2022, 14:48

Date published:

07/26/2022, 06:00