Shenkang injection improves chronic kidney disease by inhibiting multiple renin-angiotensin system genes by blocking the Wnt/β-catenin signalling pathway

pubmed: wnt1 2023-01-28


Chronic kidney disease (CKD) is a major worldwide public health problem. The increase in the number of patients with CKD and end-stage kidney disease requesting renal dialysis or transplantation will progress to epidemic proportions in the next several decades. Although blocking the renin-angiotensin system (RAS) has been used as a first-line standard therapy in patients with hypertension and CKD, patients still progress towards end-stage kidney disease, which might be closely associated with...


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Yan-Ni Wang, Hong-Jiao Liu, Li-Li Ren, Ping Suo, Liang Zou, Ya-Mei Zhang, Xiao-Yong Yu, Ying-Yong Zhao

Date tagged:

01/28/2023, 21:15

Date published:

09/05/2022, 06:00