Wnt/β-catenin signalling is required for pole-specific chromatin remodeling during planarian regeneration

pubmed: wnt1 2023-01-28

Summary:

For successful regeneration, the identity of the missing tissue must be specified according to the pre-existing tissue. Planarians are ideal for the study of the mechanisms underlying this process; the same field of cells can regrow a head or a tail according to the missing body part. After amputation, the differential activation of the Wnt/β-catenin signal specifies anterior versus posterior identity. Initially, both wnt1 and notum (Wnt inhibitor) are expressed in all wounds, but 48 hours later...

Link:

https://pubmed.ncbi.nlm.nih.gov/36653403/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20230128221328&v=2.17.9.post6+86293ac

From feeds:

Exome » pubmed: wnt1

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Authors:

Eudald Pascual-Carreras, Marta Marín-Barba, Sergio Castillo-Lara, Pablo Coronel-Córdoba, Marta Silvia Magri, Grant N Wheeler, Jose Luis Gómez-Skarmeta, Josep F Abril, Emili Saló, Teresa Adell

Date tagged:

01/28/2023, 22:13

Date published:

01/18/2023, 06:00