Efficient lung-targeted delivery of risedronate sodium/vitamin D3 conjugated PAMAM-G5 dendrimers for managing osteoporosis: Pharmacodynamics, molecular pathways and metabolomics considerations

pubmed: wnt1 2023-01-29

Summary:

AIMS: This study aims at formulating combined delivery of Risedronate sodium (RIS) and Vitamin D3 (VITD3) for augmented therapeutic outcome against osteoporosis (OP) using deep lung targeted PAMAM-G5-NH(2) dendrimers to minimize RIS gastrointestinal side effects and enhance both drugs bioavailability through absorption from the alveoli directly to the blood.

Link:

https://pubmed.ncbi.nlm.nih.gov/36174709/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20230129021612&v=2.17.9.post6+86293ac

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Exome ยป pubmed: wnt1

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Authors:

Nihal Mohamed Elmahdy Elsayyad, Iman Gomaa, Mohamed A Salem, Reham Amer, Hanan M El-Laithy

Date tagged:

01/29/2023, 02:16

Date published:

09/29/2022, 06:00