In vitro and Pharmacoinformatics-based phytochemical screening for anticancer impacts of pistachio hull essential oil on AGS, PLC/PRF/5, and CACO2 cell lines

pubmed: wnt1 2023-01-29


CONCLUSION: We showed inhibition of β-catenin protein in cancer cell lines. Four compounds of PHEO were suggested to have an inhibition effect on β-catenin and FZD7. These compounds can be useful in the treatment of gastrointestinal cancers. Altogether, the inhibitory role of β-catenin protein can be very effective and can be considered one of the therapeutic goals in the treatment of gastrointestinal cancers.


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Nahid Askari, Sepideh Parvizpour, Seyed Mohammad Bagher Marashi, Fatemeh Baghery, Soudeh Khanamani Falahati-Pour

Date tagged:

01/29/2023, 14:55

Date published:

11/08/2022, 06:00