Neuroprotective effects of oxymatrine on hypoxic-ischemic brain damage in neonatal rats by activating the Wnt/β-catenin pathway

pubmed: wnt1 2023-01-29


Neuronal apoptosis is a major pathological process associated with neurological dysfunction in neonates after hypoxic-ischemic brain damage (HIBD). Our previous study demonstrated that oxymatrine (OMT) exerts potential neuroprotective effects on neonatal rats subjected to hypoxic-ischemic insult. However, the underlying molecular mechanism remains unclear. In this study, we investigated the effects of OMT-mediated neuroprotection on neonatal HIBD by attempting to determine its effect on the...


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Xiao-Bing Lan, Yuan-Shu Ni, Ning Liu, Wei Wei, Yue Liu, Jia-Mei Yang, Lin Ma, Ru Bai, Jian Zhang, Jian-Qiang Yu

Date tagged:

01/29/2023, 17:38

Date published:

01/18/2023, 06:00