Moshen granule ameliorates membranous nephropathy by blocking intrarenal renin-angiotensin system signalling via the Wnt1/β-catenin pathway

pubmed: wnt1 2023-05-31

Summary:

CONCLUSION: This study first demonstrates that AGS mitigates podocyte injury by inhibiting the activation of RAS signalling via the Wnt1/β-catenin pathway by both pharmacological and genetic methods. Therefore, AGS might be considered a new β-catenin inhibitor that inhibits the Wnt1/β-catenin pathway to retard MN in patients.

Link:

https://pubmed.ncbi.nlm.nih.gov/37001295/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=16uwQpOeqFYN8R4TKOtwPy2utpqy9ex2oldalD2yF_fQHv2caq&fc=None&ff=20230531232115&v=2.17.9.post6+86293ac

From feeds:

Exome » pubmed: wnt1

Tags:

Authors:

Yan-Ni Wang, Hua Miao, Meng-Ru Hua, Jun-Zheng Yang, Ming Pei, Hang-Xing Yu, Li-Juan Wei, Liang Zou, Ya-Mei Zhang, Gang Cao, Ying-Yong Zhao

Date tagged:

05/31/2023, 23:21

Date published:

03/31/2023, 06:00