Ectomesenchymal <em>Six1</em> controls mandibular skeleton formation
pubmed: wnt1 2023-06-01
Summary:
Craniofacial development requires intricate cooperation between multiple transcription factors and signaling pathways. Six1 is a critical transcription factor regulating craniofacial development. However, the exact function of Six1 during craniofacial development remains elusive. In this study, we investigated the role of Six1 in mandible development using a Six1 knockout mouse model (Six1 ^(-/-) ) and a cranial neural crest-specific, Six1 conditional knockout mouse model (Six1 ^(f/f) ;...