Rspo1 and Rspo3 are required for sensory lineage neural crest formation in mouse embryos
pubmed: wnt1 2023-12-04
Summary:
CONCLUSIONS: Our results show that Rspo1 and Rspo3 are dispensable for most developmental processes involving roof plate-derived Wnt ligands, except for specification of a subtype of neural crest cells. Thus, Rspos may modulate Wnt/β-catenin signaling in a context-dependent manner.